Heart Failure: Biomarkers of Diagnosis and Prognosis
نویسنده
چکیده
The natriuretic peptides (NP), including the precursor N-terminal proBNP (NT-pro-BNP) of biologically active B-type natriuretic peptide (BNP) represent the current standard for identifying Heart Failure. In addition, the troponins serve to help identify Heart Failure patients at high risk for adverse outcomes. For nearly the last decade, emergency physicians have used these biomarkers to diagnose and risk stratify these patients. In this EMCREG-International newsletter, Heart Failure expert Dr. Frank Peacock of the Cleveland Clinic authors an excellent discussion of the scientific basis for the use of these markers, with able support by Dr. Sean Collins of the University of Cincinnati who provided peer review for the article.
منابع مشابه
Prognostic Value of Soluble ST2 (sST2) Serum Levels in Infants and Children with Heart Failure Complicating Congenital Heart Disease
Background Heart failure (HF) in infants and children with congenital heart disease (CHD) is a crucial complication with different outcomes. Many biomarkers are used as prognostic indicators. Soluble ST2 (sST2) is one of these markers studied in adults with HF. We aimed to study the prognostic value of sST2 in CHD children with HF. Materials and Methods In current case-control study, thirty-six...
متن کاملBiomarkers in acute heart failure.
The care of patients with acutely decompensated heart failure is being reshaped by the availability and understanding of several novel and emerging heart failure biomarkers. The gold standard biomarkers in heart failure are B-type natriuretic peptide and N-terminal pro-B-type natriuretic peptide, which play an important role in the diagnosis, prognosis, and management of acute decompensated hea...
متن کاملNovel Possible Biomarkers for the Cardiovascular Diseases Prognosis
Cardiovascular disease (CVD), especially heart failure (HF) as its common final pathway, is the leading cause of morbidity and mortality worldwide. Furthermore, oxidative and inflammatory processes represent fundamental underlying mechanisms for the development and progression of HF. Of interest, in recent years the development of markers with diagnostic and prognostic value for this pathology ...
متن کاملP154: Role of Exosomes as Novel Biomarkers in Diagnosis and Prognosis of Glioblastoma
Glioblastoma multiform(GBM) is the most prevalent primary brain tumor. Exosomes are extracellular vehicles for exchanging information between various cell types including cancer and normal cells. Exosomes are indicative of pathophysiological conditions of brain tumors that could be used in diagnosis and prognosis of GBM. In tumors, exosomes could carry various molecules like several miRNAs and ...
متن کاملPrognosis of emergency room stabilization of decompensated congestive heart failure with high dose lasix
Objective: Congestive heart failure (CHF) has become one of the most important health care problems in western countries. This article focuses on the outpatient diagnosis and management of heart failure. We want to compare the outcome of patients who were treated with high dose diuretics in the emergency department (ED) without admission with patients who were admitted to hospi...
متن کاملVein of Galen Aneurysmal Malformation and High-output Cardiac Failure in a Newborn
Background: Vein of Galen aneurysm (VGA) is the most common form of symptomatic cerebrovascular malformation in neonates. It develops in a fetus in the first trimester of pregnancy due to unknown reasons, but it is likely to have a genetic etiology. The prognosis of VGA is usually poor, particularly in newborns with heart failure due to high-flow intracerebral shunt. Surgery and endovascular em...
متن کامل